Mitral valve prolapse (MVP) is a common, usually benign heart disorder. The mitral valve controls blood flow between the upper (atrium) and lower (ventricle) chambers on the left side of the heart. Normally, blood should only flow in one direction, from the upper chamber into the lower chamber. In MVP, the valve flaps don’t work properly; part of the valve balloons into the atrium, which may be associated with blood flowing in the wrong direction, or leaking back into the atrium.

Prolapsed Mitral Valve
Nucleus factsheet image
© 2011 Nucleus Medical Media, Inc.

In most cases, the cause of MVP is unknown. In some cases, it appears to be an inherited genetic condition. Rarely, MVP may be caused by: