Korsakoff's syndrome is a group of symptoms that affect memory, usually in patients with alcoholism. It often occurs following Wernicke encephalopathy.

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Korsakoff syndrome is caused by a lack of vitamin B1, also known as thiamine. This is also always associated with alcoholism, since a poor diet and alcohol can prevent the body from getting enough thiamine.

Not everyone with alcoholism develops Korsakoff syndrome. A combination of genes and diet may play a role.