Progressive Multifocal Leukoencephalopathy
Pronounced: LOO-koh-en-sef-ah-LOP-ah-theeEn Español (Spanish Version)
PML is a rare progressive disease of the nervous system. It is caused by a viral infection of the cells that produce myelin.
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PML is caused by a specific papovavirus, known as JC virus. Most people get this infection in childhood and it produces no illness. It reactivates later in life in people who have suppressed immune systems. The virus damages myelin, the material that wraps around nerves. This impairs nerve function.
Last reviewedJuly 2013by Rimas Lukas, MD; Brian Randall, MD
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